Drug Standards
Medchemexpress LLC BMS-232632 sulfate | 229975-97-7 | 99.1% | 802.93 | 100 MG
Atazanavir sulfate is a highly selective and orally active HIV-1 protease inhibitor with blood-brain barrier permeability. It functions as both a substrate and inhibitor of CYP3A4 and an inhibitor of P-glycoprotein (P-gp). This compound also acts as a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM and has demonstrated efficacy in inhibiting cardiac fibrosis, hyperlipidemia, and inducing malignant glioma cell death.
- Targets HIV-1 protease, CYP3A4, P-glycoprotein, and SARS-CoV 3CLpro.
- Shows an IC50 of 3.49 μM for SARS-CoV 3CLpro.
- Attenuates hypoxia-induced cardiac fibroblast proliferation.
- Inhibits collagen I and III expression in cardiac fibroblasts.
- Induces endoplasmic reticulum stress response in glioma cells.
- Reduces collagen deposition and cardiac remodeling in MI models.
Medchemexpress LLC Sabizabulin | 1332881-26-1 | 99.0% | 50 MG
Sabizabulin (VERU-111; ABI-231) is a small-molecule tubulin inhibitor provided for research use. It disrupts microtubule dynamics and is commonly used in cellular assays and mechanism-of-action studies. Reported purity is 99.0% and the compound is available in multiple small-mass packaging options.
- Small-molecule tubulin inhibitor used in cellular and biochemical assays.
- Reported purity 99.0% for consistent experimental results.
- Available in small-mass packaging suitable for preclinical studies.
- Useful for mechanism-of-action and microtubule dynamics research.
- CAS number 1332881-26-1 for unambiguous identification.
Sigma Aldrich Fine Chemicals Biosciences Amoxicillin trihydrate British Pharmacopoeia (BP) Reference Standard | 61336-70-7 | MFCD00072029 |
Amoxicillin trihydrate British Pharmacopoeia (BP) Reference Standard | Mol Wt: 419.45 | 61336-70-7 | MFCD00072029 |
Medchemexpress LLC Mevastatin | 73573-88-3 | 99.46% | 390.51 | 100 MG
Mevastatin (Compactin) is a first HMG-CoA reductase inhibitor belonging to the statin class. It functions as a lipid-lowering agent and is known to induce apoptosis and arrest cancer cells in the G0/G1 phase. Additionally, Mevastatin increases endothelial nitric oxide synthase (eNOS) mRNA and protein levels. It exhibits antitumor activity and shows potential for the treatment of cardiovascular diseases.
- Primary inhibitor of HMG-CoA reductase
- Lipid-lowering agent
- Induces apoptosis
- Arrests cancer cells in the G0/G1 phase
- Increases eNOS mRNA and protein levels
- Exhibits antitumor activity
- Potential for cardiovascular disease treatment
- Initial source from Microorganisms (Penicillium citrinum)
- Solid, white to off-white appearance
Selleck Chemical LLC Lanabecestat (AZD3293) 5mg 1383982-64-6 LY3314814
Lanabecestat (AZD3293, LY3314814) is an oral beta-secretase 1 cleaving enzyme (BACE) inhibitor with an inhibitory constant Ki? of 0.4 nM. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
![Medchemexpress LLC 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, sodium salt (1:1), (3R,5S,6E)- | 147098-18-8 | 99.9% | 503.52 | 200 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000386888-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, sodium salt (1:1), (3R,5S,6E)- | 147098-18-8 | 99.9% | 503.52 | 200 MG
Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. It potently blocks hERG current with an IC50 of 195 nM. This compound effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
- Reduces the expression of mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein.
- Effectively lowers low-density lipoprotein (LDL) cholesterol.
- Reduces triglyceride levels.
- Decreases C-reactive protein levels.
Medchemexpress LLC Capreomycin (sulfate) | 1405-37-4 | 99.5% | 1 G
Capreomycin sulfate is a macrocyclic peptide antibiotic that inhibits phenylalanine synthesis in mycobacterial ribosomal translation. It exhibits anti-amyloidogenic and pro-fibrinolytic activities, reducing amyloid-induced cytotoxicity by inhibiting amyloid fibrillation. This product is suitable for studies related to multidrug-resistant tuberculosis, type 2 diabetes, Alzheimer's disease, and Parkinson's disease.
- Inhibits insulin fibril formation in human erythrocytes.
- Protects against amyloid fibril-induced erythrocyte damage and hemolysis.
- Destroys fibrils in erythrocytes in a time-dependent manner.
- Decreases wet lung weight and bacterial burden in the lungs of infected guinea pigs.
- Appearance: solid.
- Color: white to off-white.
- Initial source: microorganisms (Streptomyces capreolus).
- Storage: -20°C, sealed, away from moisture.
- Solubility in H2O: 100 mg/mL (requires ultrasonic).
Sigma Aldrich Fine Chemicals Biosciences Thioguanine United States Pharmacopeia (USP) Reference Standard | 154-42-7 | MFCD00233553 | 200MG
Thioguanine United States Pharmacopeia (USP) Reference Standard | Mol Wt: 167.19 | 154-42-7 | MFCD00233553 | 200MG
eMolecules 119006-77-8 | Medchem Express | Flutrimazole | 10mg | 705860563 | HY-129060 | MFCD00865591 | 346.381 | C22H16F2N2
ChemScene | 5-Hydroxy-1-methyl-1h-pyrazole-4-carboxylic acid | 100mg | 714235362 | CS-0300513 | 1255352-25-0 | MFCD21601625 | 142.114 | C5H6N2O3
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